ProSci Incorporated 于1998年成立于世界生物城之一的美国加州圣地亚哥市，从事抗体等科研试剂
的研发、生产和销售。 ProSci是世界最早和最大的细胞凋亡抗体生产厂家和供应商，公司现拥有17000
多种单、多克隆抗体，产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等
领域。公司的抗体大都经免疫亲和层析纯化，具有高纯度、高亲和力、特异性强等特点，所有的ProSci
抗体都经过了严格的验证测试和质量控制，已保证高质量的产品。ProSci的抗体广销於世界30多个国家
和地区，得到欧美日等生物医学界科研人员和生物制药公司的研发人员的广泛接受。ProSci直销的产品
和ProSci的名字已在520多篇科研论文中出现了1500多次，ProSci的经销商和客户都对ProSci产品的质量
和服务十分满意。我们的抗体可用于免疫印迹（Western blot) ，免疫组织化学（IHC），免疫细胞化学（ICC），
酶联免疫吸附实验（ELISA)和细胞流式分析（FACS)等方面。
此外，ProSci还提供标记二抗，重组蛋白，细胞和组织裂解液，细胞涂片，组织切片，多肽等产品与
抗体配套使用。ProSci在美国拥有完整的免疫学试剂开发、生产、检测的生产线，包括自己的厂房和实
验动物基地，可为您的研究提供信得过的抗体等科研试剂。

ProSci 致力于给全世界生物医药领域的科学家们提供最好的抗体等科研试剂产品，并努力成为他们研
究的首选和最好的伙伴。
这是我们一直为之努力的优质服务：
·可靠的产品质量和全面的说明书
·详细准确且不断更新的数据资料
·丰富的在线资源和全面的技术支持
·快捷可靠的物流运输
·专业的技术人员提供的优质售后服务


质量保证，我们的产品应用文献超过520 多篇，品牌名称在论文上出现1500 多次，客户中包括美国
国立卫生研究院（NIH），美国国家疾控中心（CDC），麻省理工学院（MIT），耶鲁大学以及诺华制
药等许多知名大学研究机构和制药公司，国内的客户有：中科院上海生命研究院，中国国家疾控中心，
北京协和医院，香港大学等等。



ProSci 产品应用文献统计数据
发表杂志名称 应用文献数影响因子
Journal of Experimental medicine8 14.77
Journal of Molecular Cell Biology15 13.4
Blood24 10.56
Journal of Cell Biology 11 9.92
PNAS19 9.77
Cancer research63 8.23
Human molecular genetics 48.01
Nucleic acids research 3 7.84
Journal of Neuroscience17 7.27
Journal of Cell science 86.29
The Journal of Infectious Disease26.29
Molecular and cellular biology66.19
Journal of Immunology 345.75
The Journal of Biological chemistry935.33
Molecular cancer therapeutics115.22
Journal of Virology 315.19
Molecular pharmacology74.72
Journal of Leukocyte biology 64.63
Infection and immunity 4 4.1
Journal of Bacteriology 53.73

ProSci 2011 年部分最新产品应用文献
1. Mechanisms of necroptosis in T cells. Irene L. Ch’en etc…,J. Exp. Med., Apr 2011; 208: 633 - 641.
Ripk3 antibody (ProSci Inc.).
2. SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell
Xianpei Jia etc…,J Mol Cell Biol, Aug 2011; 3: 230 - 238. Antibodies used included polyclonal anti-SOX2, STIM1
(ProSci Inc.), Orai1 (ProSci Inc.).
3. DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
Lisa S. Shock etc…, PNAS, Mar 2011; 108: 3630 - 3635. Cells were transfected using Polyjet liposomes (ProSci)
(HCT116).
4. Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and
in vivo. Yun Dai etc…, Blood, Feb 2011; 117: 1947 - 1957. expression of Bim using an antibody (ProSci).
5. Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin
lymphoma. Peter Kamper etc…, Blood, Jun 2011; 117: 6638 - 6649.
anti-GNAI3 (XW-7212; WB dilution 1:200 ProSci Incorporated).
3
6. Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88
Adeeb H. Rahman etc…, Blood, Mar 2011; 117: 3123 - 3130.
probed with rabbit anti-mouse MyD88 antibody (2127; ProSci).
7. Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-B–inducing kinase
while activating both canonical and alternative nuclear factor-B pathways
Lan V. Pham etc…,Blood, Jan 2011; 117: 200 - 210. polyclonal BR3 (ProSci).
8. Store-Operated Ca2+ Entry in Sensory Neurons: Functional Role and the Effect of Painful Nerve Injury
Geza Gemes etc…, J. Neurosci., Mar 2011; 31: 3536 - 3549.
anti-STIM1 rabbit polyclonal antibody (1:500; ProSci; catalog #4119), and anti-Orai1 rabbit polyclonal antibody (1:1000;
ProSci, catalog #4281).
9. β-Agonist-associated Reduction in RGS5 Expression Promotes Airway Smooth Muscle Hyper-responsiveness
Zhao Yang etc…, J. Biol. Chem., Apr 2011; 286: 11444 - 11455. anti-RGS5 primary antibody (Prosci, 1:250).
10. Bit-1 Mediates Integrin-dependent Cell Survival through Activation of the NFB Pathway
Genevieve S. Griffiths etc…,J. Biol. Chem., Apr 2011; 286: 14713 - 14723.
rabbit anti-Bit-1 polyclonal antibody (1:100; ProSci) or anti-FAK antibody (1:100; ProSci).
11. Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons
Jia Qi etc…,J. Immunol., Jun 2011; 186: 6417 - 6426.
rabbit polyclonal Ab against TLR3, TLR7, and TLR9 (1:1000; Prosci, Poway, CA).
12. The C Proteins of Human Parainfluenza Virus Type 1 Limit Double-Stranded RNA Accumulation That Would
Otherwise Trigger Activation of MDA5 and Protein Kinase R
Jim Boonyaratanakornkit etc…, J. Virol., Feb 2011; 85: 1495 - 1506.
HPIV1 C proteins shared by C, C Y1, and Y2 by ProSci (Poway, CA), against a synthetic peptide.
13. Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia
mutated regulates its association with sites of DNA damage
Angela E. Zolner etc…, Nucleic Acids Res., Aug 2011; 10.1093.
phospho-specific antibodies to serine 114, (ProSci Inc).
14. The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability
Ariane Scoumanne etc…, Nucleic Acids Res., Jan 2011; 39: 213 - 224.
Anti-PCBP4 was from ProSci Incorporated (Poway, CA, USA).
15. Cancer-Associated Loss-of-Function Mutations Implicate DAPK3 as a Tumor-Suppressing Kinase
John Brognard etc…, Cancer Res., Apr 2011; 71: 3152 - 3161.
DAPK3 (ZIPK) antibody was purchased from ProSci Incorporated.
16. MicroRNA-301 Mediates Proliferation and Invasion in Human Breast Cancer
Wei Shi etc…, Cancer Res., Apr 2011; 71: 2926 - 2937.
SKA2 protein was detected using a rabbit anti-SKA2 antibody (ProSci Inc.).