Prosci/ACK1 Antibody/57-363/400 ul
商品编号：
57-363
品牌：
prosci-inc
市场价：
¥7500.00
美元价：
4500.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIESREACTIVITY: | Human |
|---|---|
| HOMOLOGY: | Predictedspeciesreactivitybasedonimmunogensequence:Bovine |
| TESTEDAPPLICATIONS: | WB |
| APPLICATIONS: | ForWBstartingdilutionis:1:1000 |
| USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
| PREDICTEDMOLECULARWEIGHT: | 115kDa |
| IMMUNOGEN: | ThisACK1antibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween265-290aminoacidsfromtheCentralregionofhumanACK1. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | ThisantibodyispurifiedthroughaproteinAcolumn,followedbypeptideaffinitypurification. |
|---|---|
| PHYSICALSTATE: | Liquid |
| BUFFER: | SuppliedinPBSwith0.09%(W/V)sodiumazide. |
| CONCENTRATION: | 0.35mg/ml |
| STORAGECONDITIONS: | Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | RabbitIg |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | ActivatedCDC42kinase1,ACK-1,Tyrosinekinasenon-receptorprotein2,TNK2,ACK1 |
|---|---|
| ACCESSIONNO.: | Q07912 |
| PROTEINGINO.: | 229462980 |
| OFFICIALSYMBOL: | TNK2 |
| GENEID: | 10188 |
Background
| BACKGROUND: | ThisgeneencodesatyrosinekinasethatbindsCdc42HsinitsGTP-boundformandinhibitsboththeintrinsicandGTPase-activatingprotein(GAP)-stimulatedGTPaseactivityofCdc42Hs.Thisbindingismediatedbyauniquesequenceof47aminoacidsC-terminaltoanSH3domain.TheproteinmaybeinvolvedinaregulatorymechanismthatsustainstheGTP-boundactiveformofCdc42Hsandwhichisdirectlylinkedtoatyrosinephosphorylationsignaltransductionpathway.Severalalternativelysplicedtranscriptvariantshavebeenidentifiedfromthisgene,butthefull-lengthnatureofonlytwotranscriptvariantshasbeendetermined. |
|---|---|
| REFERENCES: | 1)Mahajan,K.,etal.J.Cell.Physiol.224(2):327-333(2010) | 2)Chua,B.T.,etal.MolOncol4(4):323-334(2010) | 3)Prieto-Echague,V.,etal.J.Biol.Chem.285(14):10605-10615(2010) | 4)Lin,Q.,etal.Mol.Cell.Biol.30(6):1541-1554(2010) |
品牌介绍
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