Prosci/β-2-微球蛋白重组蛋白/92-223/0.05 mg
商品编号：
92-223
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCESPECIES: | E.coli |
| SEQUENCE: | Ile21-Met119 |
| FUSIONTAG: | N-6Histag |
| TESTEDAPPLICATIONS: | |
| APPLICATIONS: | ThisrecombinantproteincanbeusedforBIOLOGicalassays.Forresearchuseonly. |
Properties
| PURITY: | Greaterthan95%asdeterminedbyreducingSDS-PAGE. Endotoxinlevellessthan0.1ng/ug(1IEU/ug)asdeterminedbyLALtest. |
|---|---|
| PREDICTEDMOLECULARWEIGHT: | 14kD |
| PHYSICALSTATE: | Lyophilized |
| BUFFER: | Lyophilizedfroma0.2umfilteredsolutionof20mMPB，150mMNaCl,pH7.4.Itisnotrecommendedtoreconstitutetoaconcentrationlessthan100ug/ml.DissolvethelyophilizedproteininddH2O. |
| STORAGECONDITIONS: | Lyophilizedproteinshouldbestoredat-20˚C,thoughstableatroomtemperaturefor3weeks. Reconstitutedproteinsolutioncanbestoredat4-7˚Cfor2-7days. Aliquotsofreconstitutedsamplesarestableat-20˚Cfor3months. |
AdditionalInfo
| ALTERNATENAMES: | Beta-2-Microglobulin,B2M |
|---|---|
| ACCESSIONNO.: | P61769 |
Background
| beta-2-Microglobulin(B2M)isasecretedproteinwith1Ig-likeC1-type(immunoglobulin-like)domainwhichbelongstothebeta-2-microglobulinfamily.B2Mcomponentofmajorhistocompatibilitycomplex(MHC)classImolecules,involvedinthepresentationofpeptideantigenstotheimmunesystem.Polymersofbeta2-microglobulincanbefoundintissuesfrompatientsonlong-termhemodialysis.B2Misaproteinfoundonthesurfaceofmanycellsandplentifulonthesurfaceofwhitebloodcells.SerumB2Mconcentrationisincreasedinrenaldiseases,variousmalignantdiseasesandsomeinflammatoryandautoimmunedisorders.B2Mmayadoptthefibrillarconfigurationofamyloidincertainpathologicstates.Thecapacitytoassembleintoamyloidfibrilsisconcentrationdependent.B2MhasbeenshownasaMarkerformonitoringinflammatorydiseaseactivityanditappearslikelytohaveadestructiveroleinamyloidosis-relatedarthritis.B2MmightbeinvolvedintheOA(osteoarthritis)pathogenesis.DefectsinB2Marethecauseofhypercatabolichypoproteinemia.Affectedindividualsshowmarkedreductioninserumconcentrationsofimmunoglobulinandalbumin,probablyduetorapiddegradation.B2Mcouldbeapotentialtherapeutictargetinovariancancer. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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