Prosci/BDNF Recombinant Protein/40-496/0.002 mg
商品编号：
40-496
品牌：
prosci-inc
市场价：
¥3100.00
美元价：
1860.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human, Mouse, Rat |
|---|---|
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR |
| TESTED APPLICATIONS: | |
| BIOLOGICAL ACTIVITY: | Biological activity was determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5 - 1.0 μg/mL. |
Properties
| PURITY: | Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
|---|---|
| PHYSICAL STATE: | Lyophilized |
| STORAGE CONDITIONS: | The lyophilized BDNF recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted BDNF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing BDNF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Additional Info
| ALTERNATE NAMES: | ANON2, BULN2, Brain-derived neurotrophic factor, Abrineurin, BDNF |
|---|---|
| ACCESSION NO.: | NP_001137277.1 |
| PROTEIN GI NO.: | 219842288 |
Background
| BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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