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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prosci/BD-2重组蛋白/40-131/0.02 mg
商品详细Prosci/BD-2重组蛋白/40-131/0.02 mg
Prosci/BD-2重组蛋白/40-131/0.02 mg
Prosci/BD-2重组蛋白/40-131/0.02 mg
商品编号: 40-131
品牌: prosci-inc
市场价: ¥4500.00
美元价: 2700.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
TESTED APPLICATIONS:
BIOLOGICAL ACTIVITY: Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0 - 100.0 ng/mL.

Properties

PURITY:Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:The lyophilized BD-2 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted BD-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing BD-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Additional Info

ALTERNATE NAMES:BD-2, SAP1, DEFB2, DEFB4, HBD-2, DEFB-2, DEFB102, DEFB4B, Beta-defensin 4A, Beta-defensin 2, BD-2
ACCESSION NO.:NP_004933.1
PROTEIN GI NO.:4826692

Background

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Recombinant Human BD-2 is a 4.3 kDa protein containing 41 amino acid residues.
品牌介绍
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