Prosci/BD-1重组蛋白/40-132/0.02 mg
商品编号：
40-132
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCESPECIES: | E.coli |
| SEQUENCE: | DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK |
| TESTEDAPPLICATIONS: | |
| BIOLOGICALACTIVITY: | DeterminedbyitsABIlitytochemoattractCD34+dendriticcellsusingaconcentrationrangeof100.0-1000.0ng/mL. |
Properties
| PURITY: | Greaterthan98%bySDS-PAGEgelandHPLCanalyses. Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| STORAGECONDITIONS: | ThelyophilizedBD-1recombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedBD-1isstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingBD-1recombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
AdditionalInfo
| ALTERNATENAMES: | BD1,HBD1,DEFB-1,DEFB101,BD1,Beta-defensin1,Defensin,beta1,BD-1 |
|---|---|
| ACCESSIONNO.: | NP_005209.1 |
| PROTEINGINO.: | 4885181 |
Background
| Defensins(alphaandbeta)arecationicpeptideswithabroadspectrumofantimicrobialactivitythatcompriseanimportantarmoftheinnateimmunesystem.Theα-defensinsaredistinguishedfromtheβ-defensinsbythepairingoftheirthreedisulfidebonds.Todate,fourhumanβ-defensinshavebeenidentified;BD-1,BD-2,BD-3andBD-4.β-defensinsareexpressedonsomeleukocytesandatepithelialsurfaces.Inadditiontotheirdirectantimicrobialactivities,theyarechemoattractanttowardsimmaturedendriticcellsandmemoryTcells.Theβ-defensinproteinsareexpressedastheC-terminalportionofprecursorsandarereleasedbyproteolyticcleavageofasignalsequenceand,inthecaseofBD-1(36a.a.),apropeptideregion.β-defensinscontainasix-cysteinemotifthatformsthreeintra-moleculardisulfidebonds.β-Defensinsare3-5kDapeptidesranginginsizefrom33-47aminoacidresidues.RecombinantHumanBD-1isa3.9kDaproteincontaining36aminoacidresidues. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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