Prosci/ACF Antibody/55-326/400 ul
商品编号：
55-326
品牌：
prosci-inc
市场价：
¥7500.00
美元价：
4500.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES REACTIVITY: | Human |
|---|---|
| TESTED APPLICATIONS: | IHC-P, WB |
| APPLICATIONS: | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| PREDICTED MOLECULAR WEIGHT: | 65 kDa |
| IMMUNOGEN: | This ACF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human ACF. |
| HOST SPECIES: | Rabbit |
Properties
| PURIFICATION: | This antibody is purified through a protein A column, followed by peptide affinity purification. |
|---|---|
| PHYSICAL STATE: | Liquid |
| BUFFER: | Supplied in PBS with 0.09% (W/V) sodium azide. |
| CONCENTRATION: | 0.5 mg/ml |
| STORAGE CONDITIONS: | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | Rabbit Ig |
| CONJUGATE: | Unconjugated |
Additional Info
| ALTERNATE NAMES: | APOBEC1 complementation factor, APOBEC1-stimulating protein, A1CF, ACF, ASP {ECO:0000312|EMBL:CAB947541} |
|---|---|
| ACCESSION NO.: | Q9NQ94 |
| PROTEIN GI NO.: | 74761651 |
| OFFICIAL SYMBOL: | A1CF |
| GENE ID: | 29974 |
Background
| BACKGROUND: | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. |
|---|---|
| REFERENCES: | 1) Galloway, C.A., et al. Biochem. Biophys. Res. Commun. 391(1):659-663(2010) | 2) Blanc, V., et al. Mol. Cell. Biol. 25(16):7260-7269(2005) | 3) Deloukas, P., et al. Nature 429(6990):375-381(2004) | 4) Xie, K., et al. Proc. Natl. Acad. Sci. U.S.A. 101(21):8114-8119(2004) |
品牌介绍
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