Prosci/BCL2L1 Recombinant Protein/96-056/0.1 mg
商品编号：
96-056
品牌：
prosci-inc
市场价：
¥8000.00
美元价：
4800.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | Met 1 - Arg 212 |
| FUSION TAG: | His Tag |
| TESTED APPLICATIONS: | WB |
| APPLICATIONS: | This recombinant protein can be used for WB. For research use only. |
| BIOLOGICAL ACTIVITY: | Measured by its binding ability in a functional ELISA. Immobilized human BID protein at 10μg/ml (100μl/well) can bind biotinylated human BCL2L1 protein, The EC50 of biotinylated human BCL2L1 is 6. 5 ng/mL. |
Properties
| PURITY: | >92% as determined by SDS-PAGE. |
|---|---|
| PREDICTED MOLECULAR WEIGHT: | 24.6 kDa |
| PHYSICAL STATE: | Lyopholized |
| BUFFER: | 20mM HEPES, 50mM KCl, pH 7.5 |
| STORAGE CONDITIONS: | Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles. |
Additional Info
| ALTERNATE NAMES: | BCL2L1, Bcl-XL, Bcl2-L-1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, bcl-xS |
|---|---|
| ACCESSION NO.: | AAH19307 |
Background
| Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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