4000-520-616
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4000-520-616
当前位置: 首页 > 产品中心 > Recombinant_antibodies > Prosci/ACCN4 Antibody/58-541/400 ul
商品详细Prosci/ACCN4 Antibody/58-541/400 ul
Prosci/ACCN4 Antibody/58-541/400 ul
Prosci/ACCN4 Antibody/58-541/400 ul
商品编号: 58-541
品牌: prosci-inc
市场价: ¥7500.00
美元价: 4500.00
产地: 美国(厂家直采)
公司:
产品分类: 重组抗体
公司分类: Recombinant_antibodies
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIESREACTIVITY:Human
TESTEDAPPLICATIONS:WB
APPLICATIONS:ForWBstartingdilutionis:1:1000
USERNOTE:Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
PREDICTEDMOLECULARWEIGHT:70kDa
IMMUNOGEN:ThisACCN4antibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween23-52aminoacidsfromtheN-terminalregionofhumanACCN4.
HOSTSPECIES:Rabbit

Properties

PURIFICATION:ThisantibodyispurifiedthroughaproteinAcolumn,followedbypeptideaffinitypurification.
PHYSICALSTATE:Liquid
BUFFER:SuppliedinPBSwith0.09%(W/V)sodiumazide.
CONCENTRATION:0.48mg/ml
STORAGECONDITIONS:Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
CLONALITY:Polyclonal
ISOTYPE:RabbitIg
CONJUGATE:Unconjugated

AdditionalInfo

ALTERNATENAMES:Acid-sensingionchannel4,ASIC4,Amiloride-sensitivecationchannel4,Amiloride-sensitivecationchannel4,pituitary,ASIC4,ACCN4
ACCESSIONNO.:Q96FT7
PROTEINGINO.:296434387
OFFICIALSYMBOL:ASIC4
GENEID:55515

Background

BACKGROUND:Thisgenebelongstothesuperfamilyofacid-sensingionchannels,whichareproton-gated,amiloride-sensitivesodiumchannels.Thesechannelshavebeenimplicatedinsynaptictransmission,painperceptionaswellasmechanoperception.Thisgeneispredominantlyexpressedinthepituitarygland,andwasconsideredacandidateforparoxysmaldystonicchoreoathetosis(PDC),amovementdisorder,however,nocorrelationwasfoundbetweenmutationsinthisgeneandPDC.Alternativesplicingatthislocusresultsintwotranscriptvariantsencodingdifferentisoforms.
REFERENCES:1)Donier,E.,etal.Eur.J.Neurosci.28(1):74-86(2008)
2)Lamesch,P.,etal.Genomics89(3):307-315(2007)3)Hillier,L.W.,etal.Nature434(7034):724-731(2005)4)Grunder,S.,etal.Eur.J.Hum.Genet.9(9):672-676(2001)
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