
Prosci/ACCN4 Antibody/58-541/400 ul
商品编号:
58-541
品牌:
prosci-inc
市场价:
¥7500.00
美元价:
4500.00
产品分类:
重组抗体
公司分类:
Recombinant_antibodies
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
SPECIESREACTIVITY: | Human |
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TESTEDAPPLICATIONS: | WB |
APPLICATIONS: | ForWBstartingdilutionis:1:1000 |
USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
PREDICTEDMOLECULARWEIGHT: | 70kDa |
IMMUNOGEN: | ThisACCN4antibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween23-52aminoacidsfromtheN-terminalregionofhumanACCN4. |
HOSTSPECIES: | Rabbit |
Properties
PURIFICATION: | ThisantibodyispurifiedthroughaproteinAcolumn,followedbypeptideaffinitypurification. |
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PHYSICALSTATE: | Liquid |
BUFFER: | SuppliedinPBSwith0.09%(W/V)sodiumazide. |
CONCENTRATION: | 0.48mg/ml |
STORAGECONDITIONS: | Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures. |
CLONALITY: | Polyclonal |
ISOTYPE: | RabbitIg |
CONJUGATE: | Unconjugated |
AdditionalInfo
ALTERNATENAMES: | Acid-sensingionchannel4,ASIC4,Amiloride-sensitivecationchannel4,Amiloride-sensitivecationchannel4,pituitary,ASIC4,ACCN4 |
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ACCESSIONNO.: | Q96FT7 |
PROTEINGINO.: | 296434387 |
OFFICIALSYMBOL: | ASIC4 |
GENEID: | 55515 |
Background
BACKGROUND: | Thisgenebelongstothesuperfamilyofacid-sensingionchannels,whichareproton-gated,amiloride-sensitivesodiumchannels.Thesechannelshavebeenimplicatedinsynaptictransmission,painperceptionaswellasmechanoperception.Thisgeneispredominantlyexpressedinthepituitarygland,andwasconsideredacandidateforparoxysmaldystonicchoreoathetosis(PDC),amovementdisorder,however,nocorrelationwasfoundbetweenmutationsinthisgeneandPDC.Alternativesplicingatthislocusresultsintwotranscriptvariantsencodingdifferentisoforms. |
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REFERENCES: | 1)Donier,E.,etal.Eur.J.Neurosci.28(1):74-86(2008) | 2)Lamesch,P.,etal.Genomics89(3):307-315(2007) | 3)Hillier,L.W.,etal.Nature434(7034):724-731(2005) | 4)Grunder,S.,etal.Eur.J.Hum.Genet.9(9):672-676(2001) |
品牌介绍
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