Prosci/ACCN3 Antibody/60-330/400 ul
商品编号：
60-330
品牌：
prosci-inc
市场价：
¥7500.00
美元价：
4500.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES REACTIVITY: | Human |
|---|---|
| TESTED APPLICATIONS: | WB |
| APPLICATIONS: | For WB starting dilution is: 1:1000 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| PREDICTED MOLECULAR WEIGHT: | 59 kDa |
| IMMUNOGEN: | This ACCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3. |
| HOST SPECIES: | Rabbit |
Properties
| PURIFICATION: | This antibody is purified through a protein A column, followed by peptide affinity purification. |
|---|---|
| PHYSICAL STATE: | Liquid |
| BUFFER: | Supplied in PBS with 0.09% (W/V) sodium azide. |
| CONCENTRATION: | 0.5 mg/ml |
| STORAGE CONDITIONS: | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | Rabbit Ig |
| CONJUGATE: | Unconjugated |
Additional Info
| ALTERNATE NAMES: | Acid-sensing ion channel 3, ASIC3, hASIC3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Testis sodium channel 1, hTNaC1, ASIC3, ACCN3, SLNAC1, TNAC1 |
|---|---|
| ACCESSION NO.: | Q9UHC3 |
| PROTEIN GI NO.: | 82582992 |
| OFFICIAL SYMBOL: | ASIC3 |
| GENE ID: | 9311 |
Background
| BACKGROUND: | This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms. |
|---|---|
| REFERENCES: | 1) Borzan, J., et al. Anesthesiology 113(3):647-654(2010) | 2) Wu, S., et al. Clin. Chim. Acta 411 (15-16), 1132-1136 (2010) : | 3) Ko, Y.L., et al. J. Hypertens. 26(11):2154-2160(2008) | 4) Su, X., et al. J. Biol. Chem. 281(48):36960-36968(2006) |
品牌介绍
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