Prosci/ATG3重组蛋白/90-321/50微克
商品编号:
90-321
品牌:
prosci-inc
市场价:
¥4500.00
美元价:
2700.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
SPECIES: | Human |
---|---|
SOURCESPECIES: | E.coli |
SEQUENCE: | RecombinanthumanATG3(aa1-337)fusedtoaHis-tag. |
FUSIONTAG: | HisTag |
TESTEDAPPLICATIONS: | |
APPLICATIONS: | Thisrecombinantproteinsisforresearchuseonly. |
BIOLOGICALACTIVITY: | N/A |
Properties
PURITY: | >95%(SDS-PAGE) |
---|---|
PHYSICALSTATE: | Lyophilized |
BUFFER: | Lyophilizedfrom20mMTRIS-HCl,pH8.0,containing150mMsodiumchlorideandproteaseinhibitor(SigmaS8830,1xconcentration). |
CONCENTRATION: | 0.5mg/mlafterreconstitution. |
STORAGECONDITIONS: | Stableforatleast1yearafterreceiptwhenstoredat-20˚C. |
AdditionalInfo
ALTERNATENAMES: | Autophagy-relatedProtein3,Ubiquitin-like-conjugatingEnzymeATG3,APG3-like,PC3-96 |
---|---|
ACCESSIONNO.: | NM_022488 |
PROTEINGINO.: | 523704483 |
Background
ATG3(Autophagy-relatedprotein3;APG3-like;PC3-96)isanubiquitousmemberoftheATG3familyofproteins.Itbelongstotheautophaginproteinfamilyimportantinautophagy,thebiologicalprocesswhichisinvolvedindegradationofendogenousproteinsanddamagedorganelles.ATG3isanE2-likeenzymeinvolvedintheinitialstagesofautophagocytosis,autophagyandmitochondrialhomeostasis.Autophagocytosisisastarvation-inducedprocessresponsIBLeforthetransportofcytoplasmicproteinstothelysosome/vacuole.ItcatalyzesthetransferofATG7-boundATG8(LC3;GATE16;GABA-RAPinmammals)tophosphatidylethanolamine,whichisessentialforautophagy.ItactsasanautocatalyticE2-likeenzyme,catalyzingtheconjugationofATG12toitself.TheATG12conjugationtoATG3playsaroleinmitochondrialhomeostasisbutnotinautophagy. |
品牌介绍
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