Prosci/ATG12 Recombinant Protein/95-125/0.05 mg
商品编号：
95-125
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Mouse |
|---|---|
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | aa 101 - 141 |
| FUSION TAG: | Fusion Partner: C-terminal His-tag |
| TESTED APPLICATIONS: | ELISA, WB |
| APPLICATIONS: | This recombinant protein can be used for WB and ELISA. For research use only. |
| BIOLOGICAL ACTIVITY: | N/A |
Properties
| PURITY: | ~95% |
|---|---|
| PREDICTED MOLECULAR WEIGHT: | 10 kDa (Calculated) |
| PHYSICAL STATE: | Liquid |
| BUFFER: | 1X PBS containing 0.1% SDS |
| STORAGE CONDITIONS: | Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Additional Info
| ALTERNATE NAMES: | ATG12 Antibody: APG12, FBR93, APG12L, HAPG12, APG12, Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like |
|---|---|
| ACCESSION NO.: | Q9CQY1 |
| PROTEIN GI NO.: | 17366729 |
Background
| Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1 (3). ATG12, another member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy (4). This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells (5). ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7 (6). |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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