Prosci/Artemin重组蛋白/40-113/0.02 mg
商品编号：
40-113
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG |
| TESTED APPLICATIONS: | |
| BIOLOGICAL ACTIVITY: | Biological Activity determined by it's ability to promote survival and neurite outgrowth and dorsal root ganglion neurons. |
Properties
| PURITY: | Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
|---|---|
| PHYSICAL STATE: | Lyophilized |
| STORAGE CONDITIONS: | The lyophilized Artemin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Artemin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Artemin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Additional Info
| ALTERNATE NAMES: | EVN, NBN, ENOVIN, EVN, Artemin, Enovin |
|---|---|
| ACCESSION NO.: | NP_001129687.1 |
| PROTEIN GI NO.: | 209977029 |
Background
| Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons. The functional human Artemin ligand is a disulfide-linked homodimer, of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration. Recombinant human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits. |
品牌介绍
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