Prosci/Artemin重组蛋白/40-113/0.005 mg
商品编号：
40-113
品牌：
prosci-inc
市场价：
¥3100.00
美元价：
1860.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCESPECIES: | E.coli |
| SEQUENCE: | AGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG |
| TESTEDAPPLICATIONS: | |
| BIOLOGICALACTIVITY: | BiologicalActivitydeterminedbyit"sABIlitytopromotesurvivalandneuriteoutgrowthanddorsalrootganglionneurons. |
Properties
| PURITY: | Greaterthan98%bySDS-PAGEgelandHPLCanalyses. Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| STORAGECONDITIONS: | ThelyophilizedArteminrecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedArteminisstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingArteminrecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
AdditionalInfo
| ALTERNATENAMES: | EVN,NBN,ENOVIN,EVN,Artemin,Enovin |
|---|---|
| ACCESSIONNO.: | NP_001129687.1 |
| PROTEINGINO.: | 209977029 |
Background
| Arteminisadisulfide-linkedhomodimericneurotrophicfactorstructurallyrelatedtoGDNF,Artemin,NeurturinandPersephin.Theseproteinsbelongtothecysteine-knotsuperfamilyofgrowthfactorsthatassumestabledimericproteinstructures.Artemin,GDNF,PersephinandNeurturinallsignalthroughamulticomponentreceptorsystem,composedofRET(receptortyrosinekinase)andoneofthefourGFRalpha(alpha1-alpha4)receptors.ArteminprefersthereceptorGFRalpha3-RET,butwilluseotherreceptorsasanalternative.Arteminsupportsthesurvivalofallperipheralgangliasuchassympathetic,neuralcrestandplacodallyderivedsensoryneurons,anddompaminergicmidbrainneurons.ThefunctionalhumanArteminligandisadisulfide-linkedhomodimer,oftwo12.0kDapolypeptidemonomers.Eachmonomercontainssevenconservedcysteineresidues,oneofwhichisusedforinterchaindisulfidebridgingandtheothersareinvolvedinintramolecularringformationknownasthecysteineknotconfiguration.RecombinanthumanArteminisa24.2kDa,disulfide-linkedhomodimerformedbytwoidentical113aminoacidsubunits. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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