Prosci/APRIL重组蛋白/40-302/0.01 mg
商品编号：
40-302
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCESPECIES: | High-5Insectcells |
| SEQUENCE: | AVLTQKQKKQHSVLHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSPHGTFLGFVKL |
| TESTEDAPPLICATIONS: | |
| BIOLOGICALACTIVITY: | TestedbyitsABIlitytoinduceIgMsecretionbyCpG/CD40LtreatedhumannaiveBcells,ataconcentrationof500ng/mL. |
Properties
| PURITY: | Greaterthan95%bySDS-PAGEgelandHPLCanalyses. Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| STORAGECONDITIONS: | ThelyophilizedAPRILrecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedAPRILisstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingAPRILrecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
AdditionalInfo
| ALTERNATENAMES: | APRIL,CD256,TALL2,ZTNF2,TALL-2,TRDL-1,UNQ383/PRO715,APRIL,Tumornecrosisfactorligandsuperfamilymember13,Aproliferation-inducingligand |
|---|---|
| ACCESSIONNO.: | NP_001185551.1 |
| PROTEINGINO.: | 310750385 |
Background
| APRIL,amemberoftheTNFsuperfamily,isexpressedinmonocytes,macrophages,certaintransformedcelllines,certaincancersofcolon,andlymphoidtissues.APRIL,alongwithanotherTNFfamilymember,BAFF,competefortworeceptors,TACIandBCMA.ARPILhastheabilitytostimulateproliferationofvarioustumorcelllinesincludingJurkatTcellsandMCF-7carcinomacells.LikeBAFF,APRILalsostimulatestheproliferationofBandTcells.ThehumanAPRILgenecodesforatleastfouralternativelysplicedtranscriptionalvariants,whichgiverisetodifferentisoformsoftheAPRILprecursorprotein.Allisoformscanbecleavedbytheprotease,furin,toreleaseasolubleC-terminalfragment,whichcomprisestheTNFlikereceptorbindingoftheAPRILprecursor.RecombinanthumanAPRILisasoluble16.3kDaprotein,consistingof146aminoacidresidues. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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