Prosci/APRIL Recombinant Protein/40-453/0.02 mg
商品编号：
40-453
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Murine |
|---|---|
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | MRREVSRLQR SGGPSQKQGE RPWQSLWEQS PDVLEAWKDG AKSRRRRAVL TQKHKKKHSV LHLVPVNITS KDSDVTEVMW QPVLRRGRGL EAQGDIVRVW DTGIYLLYSQ VLFHDVTFTM GQVVSREGQG RRETLFRCIR SMPSDPDRAY NSCYSAGVFH LHQGDIITVK IPRANAKLSL SPHGTFLGFV KL |
| TESTED APPLICATIONS: | |
| BIOLOGICAL ACTIVITY: | Biological activity was measured by its ability to induce cell proliferation of activated T cells. |
Properties
| PURITY: | Greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
|---|---|
| PHYSICAL STATE: | Lyophilized |
| STORAGE CONDITIONS: | The lyophilized APRIL recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted APRIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing APRIL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Additional Info
| ALTERNATE NAMES: | April, Tall2, Trdl1, 2310026N09Rik, April, Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand, APRIL |
|---|---|
| ACCESSION NO.: | NP_001152977.1 |
| PROTEIN GI NO.: | 226958398 |
Background
| APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. APRIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Recombinant murine APRIL is a soluble 21.9 kDa protein, consisting of 192 amino acid residues. |
品牌介绍
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