Prosci/ApoA-I重组蛋白/40-139/0.02 mg
商品编号：
40-139
品牌：
prosci-inc
市场价：
¥3100.00
美元价：
1860.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCESPECIES: | E.coli |
| SEQUENCE: | MDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ |
| TESTEDAPPLICATIONS: |
Properties
| PURITY: | Greaterthan97%bySDS-PAGEgelandHPLCanalyses. Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| STORAGECONDITIONS: | ThelyophilizedApoA-Irecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedApoA-Iisstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingApoA-Irecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
AdditionalInfo
| ALTERNATENAMES: | ApolipoproteinA-I,ApolipoproteinA1,Apo-AI |
|---|---|
| ACCESSIONNO.: | NP_000030.1 |
| PROTEINGINO.: | 4557321 |
Background
| ApoA-Iisa29.0kDaproteinproducedintheliverandintestine,andsecretedasthepredominantconstituentofnascenthigh-densitylipoprotein(HDL)particle.ApoA-I,whichisfoundexclusivelyinHDL,hasauniqueABIlitytocaptureandsolubilizefreecholesterol.ThisapoA-IabilityenablesHDLtoremoveexcessperipheralcholesterolandreturnittotheliverforrecyclingandexcretion.Thisprocess,calledreversecholesteroltransport,isthoughtoinhibitatherogenesis.ForthisreasonHDLisalsoknownasthe"goodcholesterol.”ThetherapeuticpotentialofapoA-Ihasbeenrecentlyassessedinpatientswithacutecoronarysyndromes,usingarecombinantformofanaturallyoccurringvariantofapoA-I(calledapoA-IMilano).TheavailabilityofrecombinantnormalapoA-IshouldfacilitatefurtherinvestigationintothepotentialusefulnessofapoA-Iinpreventingatheroscleroticvasculardiseases.RecombinanthumanApoA-Iisa28.2kDaproteinof244aminoacidresidues. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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