4000-520-616
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4000-520-616
当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prosci/Apo A1重组蛋白/96-031/0.05 mg
商品详细Prosci/Apo A1重组蛋白/96-031/0.05 mg
Prosci/Apo A1重组蛋白/96-031/0.05 mg
Prosci/Apo A1重组蛋白/96-031/0.05 mg
商品编号: 96-031
品牌: prosci-inc
市场价: ¥9000.00
美元价: 5400.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIES:Human
SOURCESPECIES:HEK293cells
SEQUENCE:Arg19-Gln267
FUSIONTAG:HisTag
TESTEDAPPLICATIONS:WB
APPLICATIONS:ThisrecombinantproteincanbeusedforWB.Forresearchuseonly.
BIOLOGICALACTIVITY:ImmobilizedHumanApoAIat10μg/mL(100μl/well)canbindbiotinylatedhumanSCARB1.TheEC50ofbiotinylatedhumanSCARB1is10-100ng/mL.

Properties

PURITY:>95%asdeterminedbySDS-PAGE.
PREDICTEDMOLECULARWEIGHT:29kDa
PHYSICALSTATE:Lyopholized
BUFFER:PBS,pH7.4
STORAGECONDITIONS:LyophilizedProteinshouldbestoredat-20˚Corlowerforlongtermstorage.Uponreconstitution,workingaliquotsshouldbestoredat-20˚Cor-70˚C.Avoidrepeatedfreeze-thawcycles.

AdditionalInfo

ALTERNATENAMES:ApolipoproteinA-I,APOA1,MGC117399
ACCESSIONNO.:NP_000030.1

Background

ApoA1isalsoknownasapolipoproteinA-I,ApoA-I,andisthemajorproteincomponentofhighdensitylipoprotein(HDL)inplasma.Ithasaspecificroleinlipidmetabolism.ChylomicronssecretedfromtheintestinalenterocytealsocontainApoA1butitisquicklytransferredtoHDLinthebloodstream.Theproteinpromotescholesteroleffluxfromtissuestotheliverforexcretion.Itisacofactorforlecithincholesterolacyltransferase(LCAT)whichisresponsIBLefortheformationofmostplasmacholesterylesters.ApoA-Iwasalsoisolatedasaprostacyclin(PGI2)stABIlizingfactor,andthusmayhaveananticlottingeffect.DefectsinthegeneencodingitareassociatedwithHDLdeficiencies,includingTangierdisease,andwithsystemicnon-neuropathicamyloidosis.Inaddition,ithasbeenshownthatApoA1isimplicatedintheanti-endotoxinfunctionofHDLviainteractionwithlipopolysaccharideorendotoxin.
品牌介绍
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