Prosci/ABCC9抗体/59-820/400微升
商品编号:
59-820
品牌:
prosci-inc
市场价:
¥7500.00
美元价:
4500.00
产品分类:
重组抗体
公司分类:
Recombinant_antibodies
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
SPECIES REACTIVITY: | Human, Mouse |
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TESTED APPLICATIONS: | WB |
APPLICATIONS: | For WB starting dilution is: 1:1000 |
USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
PREDICTED MOLECULAR WEIGHT: | 174 kDa |
IMMUNOGEN: | This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9. |
HOST SPECIES: | Rabbit |
Properties
PURIFICATION: | This antibody is purified through a protein A column, followed by peptide affinity purification. |
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PHYSICAL STATE: | Liquid |
BUFFER: | Supplied in PBS with 0.09% (W/V) sodium azide. |
CONCENTRATION: | 0.488 mg/ml |
STORAGE CONDITIONS: | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
CLONALITY: | Polyclonal |
ISOTYPE: | Rabbit Ig |
CONJUGATE: | Unconjugated |
Additional Info
ALTERNATE NAMES: | ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, ABCC9, SUR2 |
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ACCESSION NO.: | O60706 |
OFFICIAL SYMBOL: | ABCC9 |
GENE ID: | 10060 |
Background
BACKGROUND: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion. |
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REFERENCES: | 1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) | 2) Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010) | 3) Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010) | 4) Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391(1):974-978(2010) |
品牌介绍
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