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当前位置: 首页 > 产品中心 > Recombinant_antibodies > Prosci/ABCC4抗体/62-908/400微升
商品详细Prosci/ABCC4抗体/62-908/400微升
Prosci/ABCC4抗体/62-908/400微升
Prosci/ABCC4抗体/62-908/400微升
商品编号: 62-908
品牌: prosci-inc
市场价: ¥7500.00
美元价: 4500.00
产地: 美国(厂家直采)
公司:
产品分类: 重组抗体
公司分类: Recombinant_antibodies
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIES REACTIVITY:Human
TESTED APPLICATIONS:WB
APPLICATIONS:For WB starting dilution is: 1:1000
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
PREDICTED MOLECULAR WEIGHT:150 kDa
IMMUNOGEN:This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1145 amino acids from the C-terminal region of human ABCC4.
HOST SPECIES:Rabbit

Properties

PURIFICATION:This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION:2 mg/ml
STORAGE CONDITIONS:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Polyclonal
ISOTYPE:Rabbit Ig
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:Multidrug resistance-associated protein 4, ATP-binding cassette sub-family C member 4, MRP/cMOAT-related ABC transporter, Multi-specific organic anion transporter B, MOAT-B, ABCC4, MRP4
ACCESSION NO.:O15439
OFFICIAL SYMBOL:ABCC4
GENE ID:10257

Background

BACKGROUND:ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
REFERENCES: 1) Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747(1998)
2) Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004(2002) 3) Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547(1997) 4) Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669(2008)
品牌介绍
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