
Prosci/ABCC4抗体/62-908/400微升
商品编号:
62-908
品牌:
prosci-inc
市场价:
¥7500.00
美元价:
4500.00
产品分类:
重组抗体
公司分类:
Recombinant_antibodies
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
SPECIES REACTIVITY: | Human |
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TESTED APPLICATIONS: | WB |
APPLICATIONS: | For WB starting dilution is: 1:1000 |
USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
PREDICTED MOLECULAR WEIGHT: | 150 kDa |
IMMUNOGEN: | This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1145 amino acids from the C-terminal region of human ABCC4. |
HOST SPECIES: | Rabbit |
Properties
PURIFICATION: | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis |
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PHYSICAL STATE: | Liquid |
BUFFER: | Supplied in PBS with 0.09% (W/V) sodium azide. |
CONCENTRATION: | 2 mg/ml |
STORAGE CONDITIONS: | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
CLONALITY: | Polyclonal |
ISOTYPE: | Rabbit Ig |
CONJUGATE: | Unconjugated |
Additional Info
ALTERNATE NAMES: | Multidrug resistance-associated protein 4, ATP-binding cassette sub-family C member 4, MRP/cMOAT-related ABC transporter, Multi-specific organic anion transporter B, MOAT-B, ABCC4, MRP4 |
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ACCESSION NO.: | O15439 |
OFFICIAL SYMBOL: | ABCC4 |
GENE ID: | 10257 |
Background
BACKGROUND: | ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. |
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REFERENCES: | 1) Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747(1998) | 2) Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004(2002) | 3) Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547(1997) | 4) Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669(2008) |
品牌介绍
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