Prosci/ABCC1抗体/62-353/400微升
商品编号:
62-353
品牌:
prosci-inc
市场价:
¥7500.00
美元价:
4500.00
产品分类:
重组抗体
公司分类:
Recombinant_antibodies
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
| SPECIESREACTIVITY: | Human |
|---|---|
| HOMOLOGY: | Predictedspeciesreactivitybasedonimmunogensequence:Bovine,Monkey,Mouse |
| TESTEDAPPLICATIONS: | Flow,WB |
| APPLICATIONS: | ForWBstartingdilutionis:1:1000 ForFACSstartingdilutionis:1:10~50 |
| USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
| PREDICTEDMOLECULARWEIGHT: | 172kDa |
| IMMUNOGEN: | ThisABCC1antibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween1247-1275aminoacidsfromtheC-terminalregionofhumanABCC1. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | ThisantibodyispreparedbySaturatedAmmoniumSulfate(SAS)precipitationfollowedbydialysis |
|---|---|
| PHYSICALSTATE: | Liquid |
| BUFFER: | SuppliedinPBSwith0.09%(W/V)sodiumazide. |
| CONCENTRATION: | 2mg/ml |
| STORAGECONDITIONS: | Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | RabbitIg |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | Multidrugresistance-associatedprotein1,ATP-bindingcassettesub-familyCmember1,LeukotrieneC(4)transporter,LTC4transporter,ABCC1,MRP,MRP1 |
|---|---|
| ACCESSIONNO.: | P33527 |
| PROTEINGINO.: | 296439301 |
| OFFICIALSYMBOL: | ABCC1 |
| GENEID: | 4363 |
Background
| BACKGROUND: | ABCC1isamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCgenearedividedintosevendistinctsubfamilies(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).ThisfulltransporterisamemberoftheMRPsubfamilywhichisinvolvedinmulti-drugresistance.Thisproteinfunctionsasamultispecificorganicaniontransporter,withoxidizedglutatione,cysteinylleukotrienes,andactivatedaflatoxinB1assubstrates.Thisproteinalsotransportsglucuronidesandsulfateconjugatesofsteroidhormonesandbilesalts. |
|---|---|
| REFERENCES: | 1)Siedlinski,M.,Pharmacogenet.Genomics19(9),675-684(2009) |
品牌介绍
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