Prosci/ABCB8抗体/25-886/50微克
商品编号：
25-886
品牌：
prosci-inc
市场价：
¥6500.00
美元价：
3900.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIESREACTIVITY: | Human,Mouse |
|---|---|
| TESTEDAPPLICATIONS: | ELISA,WB |
| APPLICATIONS: | ABCB8antibodycanbeusedfordetectionofABCB8byELISAat1:62500.ABCB8antibodycanbeusedfordetectionofABCB8bywesternblotat1μg/mL,andHRPconjugatedsecondaryantibodyshouldbediluted1:50,000-100,000. |
| USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
| POSITIVECONTROL: | 1)Cat.No.XBL-10407-FetalHeartTissueLysate |
| PREDICTEDMOLECULARWEIGHT: | 79kDa |
| IMMUNOGEN: | AntibodyproducedinrabbitsimmunizedwithasyntheticpeptidecorrespondingaregionofhumanABCB8. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | Antibodyispurifiedbypeptideaffinitychromatographymethod. |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| BUFFER: | AntibodyislyophilizedinPBSbufferwith2%sucrose.Add50μLofdistilledwater.Finalantibodyconcentrationis1mg/mL. |
| CONCENTRATION: | 1mg/ml |
| STORAGECONDITIONS: | Forshortperiodsofstorage(days)storeat4˚C.Forlongerperiodsofstorage,storeABCB8antibodyat-20˚C.Aswithanyantibodyavoidrepeatfreeze-thawcycles. |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | ABCB8,EST328128,M-ABC1,MABC1 |
|---|---|
| ACCESSIONNO.: | NP_009119 |
| PROTEINGINO.: | 156105685 |
| OFFICIALSYMBOL: | ABCB8 |
| GENEID: | 11194 |
Background
| BACKGROUND: | Themembrane-associatedproteinABCB8isamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCproteinsaredividedintosevendistinctsubfamilies(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).ABCB8isamemberoftheMDR/TAPsubfamily.MembersoftheMDR/TAPsubfamilyareinvolvedinmultidrugresistanceaswellasantigenpresentation.Thefunctionofthishalf-transporterhasnotyetbeendetermined;however,itmayinvolvethecompartmentalizationandtransportofheme,aswellaspeptides,fromthemitochondriatothenucleusandcytosol.Thisproteinmayalsoplayaroleinthetransportofphospholipidsintomitochondrialmembranes.Themembrane-associatedproteinencodedbythisgeneisamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCgenesaredividedintosevendistinctsubfamilies(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).ThisproteinisamemberoftheMDR/TAPsubfamily.MembersoftheMDR/TAPsubfamilyareinvolvedinmultidrugresistanceaswellasantigenpresentation.Thefunctionofthishalf-transporterhasnotyetbeendetermined;however,itmayinvolvethecompartmentalizationandtransportofheme,aswellaspeptides,fromthemitochondriatothenucleusandcytosol.Thisproteinmayalsoplayaroleinthetransportofphospholipidsintomitochondrialmembranes. |
|---|---|
| REFERENCES: | 1)Saito,S.,(2002)J.Hum.Genet.47(1),38-50. |
品牌介绍
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