Prosci/ABCB7抗体/62-131/400微升
商品编号：
62-131
品牌：
prosci-inc
市场价：
¥7500.00
美元价：
4500.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIESREACTIVITY: | Human |
|---|---|
| HOMOLOGY: | Predictedspeciesreactivitybasedonimmunogensequence:Mouse |
| TESTEDAPPLICATIONS: | IHC-P,WB |
| APPLICATIONS: | ForWBstartingdilutionis:1:1000 ForIHC-Pstartingdilutionis:1:50~100 |
| USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
| PREDICTEDMOLECULARWEIGHT: | 83kDa |
| IMMUNOGEN: | ThisABCB7antibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween718-746aminoacidsfromtheC-terminalregionofhumanABCB7. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | ThisantibodyispreparedbySaturatedAmmoniumSulfate(SAS)precipitationfollowedbydialysis |
|---|---|
| PHYSICALSTATE: | Liquid |
| BUFFER: | SuppliedinPBSwith0.09%(W/V)sodiumazide. |
| CONCENTRATION: | 2mg/ml |
| STORAGECONDITIONS: | Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | RabbitIg |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | ATP-bindingcassettesub-familyBmember7,mitochondrial,ATP-bindingcassettetransporter7,ABCtransporter7protein,ABCB7,ABC7 |
|---|---|
| ACCESSIONNO.: | O75027 |
| OFFICIALSYMBOL: | ABCB7 |
| GENEID: | 22 |
Background
| BACKGROUND: | Themembrane-associatedproteinABCB7isamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCgenesaredividedintosevendistinctsubfamilies(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).ThisproteinisamemberoftheMDR/TAPsubfamily.MembersoftheMDR/TAPsubfamilyareinvolvedinmultidrugresistanceaswellasantigenpresentation.Thisgeneencodesahalf-transporterinvolvedinthetransportofhemefromthemitochondriatothecytosol.Withiron/sulfurclusterprecursorsasitssubstrates,thisproteinmayplayaroleinmetalhomeostasis.MutationsinthisgenehavebeenimplicatedinX-linkedsideroblasticanemiawithataxia. |
|---|---|
| REFERENCES: | 1)Allikmets,R.,etal.,Hum.Mol.Genet.8(5):743-749(1999). | 2)Csere,P.,etal.,FEBSLett.441(2):266-270(1998). | 3)Mao,M.,etal.,Proc.Natl.Acad.Sci.U.S.A.95(14):8175-8180(1998). | 4)Shimada,Y.,etal.,J.Hum.Genet.43(2):115-122(1998). |
品牌介绍
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