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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prosci/Angiopoietin-1 Recombinant Protein/90-007/10 ug
商品详细Prosci/Angiopoietin-1 Recombinant Protein/90-007/10 ug
Prosci/Angiopoietin-1 Recombinant Protein/90-007/10 ug
Prosci/Angiopoietin-1 Recombinant Protein/90-007/10 ug
商品编号: 90-007
品牌: prosci-inc
市场价: ¥6000.00
美元价: 3600.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIES:Human
SOURCE SPECIES:CHO cells
SEQUENCE:Human angiopoietin-1 (aa 20-498) is fused at the N-terminus to a DDDDK-tag.
FUSION TAG:DDDDK Tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY: Induces phosphorylation of Tie-2 in primary cultured human vascular endothelial cells (HUVECs). The protein forms mainly tetrameric structures.

Properties

PURITY:>90% (SDS-PAGE)
PHYSICAL STATE:Liquid
BUFFER:0.2um-filtered solution in PBS containing 0.02% CHAPS.
CONCENTRATION:~0.2mg/ml
STORAGE CONDITIONS:Working aliquots are stable for up to 3 months when stored at -20˚C.

Additional Info

ALTERNATE NAMES:Ang-1, Ang1, Angpt1
ACCESSION NO.:Q15389
PROTEIN GI NO.:20532340

Background

Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
品牌介绍
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