Prosci/α-内硫醚重组蛋白/96-265/0.1 mg
商品编号：
96-265
品牌：
prosci-inc
市场价：
¥6500.00
美元价：
3900.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Human |
|---|---|
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | Ser 2 - Glu 121 |
| FUSION TAG: | His Tag |
| TESTED APPLICATIONS: | |
| APPLICATIONS: | This recombinant protein can be used for WB. For research use only. |
Properties
| PURITY: | >90% as determined by SDS-PAGE. |
|---|---|
| PREDICTED MOLECULAR WEIGHT: | 14.2 kDa |
| PHYSICAL STATE: | Lyopholized |
| BUFFER: | PBS, pH 7.4 |
| STORAGE CONDITIONS: | Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles. |
Additional Info
| ALTERNATE NAMES: | ENSA, Alpha-endosulfine, ARPP-19e, endosulfine Alpha |
|---|---|
| ACCESSION NO.: | AAH00436 |
Background
| Alpha-endosulfine (ENSA),a member of the endosulfine family, is also known as ARPP-19e,which is widely expressed with high levels in skeletal muscle and brain and lower levels in the pancreas. ENSA is a protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, ENSA is able to specifically interact with PPP2R2D (PR55-delta) and inhibit its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). ENSA acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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