Prosci/ALK-1重组蛋白/92-565/0.05 mg
商品编号：
92-565
品牌：
prosci-inc
市场价：
¥4500.00
美元价：
2700.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Mouse |
|---|---|
| SOURCESPECIES: | HumanCells |
| SEQUENCE: | Asp23-Pro119 |
| FUSIONTAG: | C-Fctag |
| TESTEDAPPLICATIONS: | |
| APPLICATIONS: | ThisrecombinantproteincanbeusedforBIOLOGicalassays.Forresearchuseonly. |
Properties
| PURITY: | Greaterthan95%asdeterminedbyreducingSDS-PAGE. Endotoxinlevellessthan0.1ng/ug(1IEU/ug)asdeterminedbyLALtest. |
|---|---|
| PREDICTEDMOLECULARWEIGHT: | 38.1kD |
| PHYSICALSTATE: | Lyophilized |
| BUFFER: | Lyophilizedfroma0.2umfilteredsolutionofPBS,pH7.4.Itisnotrecommendedtoreconstitutetoaconcentrationlessthan100ug/ml.DissolvethelyophilizedproteininddH2O. |
| STORAGECONDITIONS: | Lyophilizedproteinshouldbestoredat-20˚C,thoughstableatroomtemperaturefor3weeks. Reconstitutedproteinsolutioncanbestoredat4-7˚Cfor2-7days. Aliquotsofreconstitutedsamplesarestableat-20˚Cfor3months. |
AdditionalInfo
| ALTERNATENAMES: | Serine/threonine-proteinkinasereceptorR3,SKR3,Activinreceptor-likekinase1,ALK-1,TGF-BsuperfamilyreceptortypeI,TSR-I,ACVRL1,activinAreceptortypeII-like1,activinAreceptor |
|---|---|
| ACCESSIONNO.: | Q61288 |
Background
| ActivinReceptor-LikeKinase1(ALK-1)isatypeIcell-surfacereceptorfortheTGF-betasuperfamilyofligands,whichmediatessignalingofBMP9(bonemorphogeneticprotein)andBMP10.ALK1signalingisnecessaryforangiogenesisduringembryogenesis,woundhealing,andtumorgrowth.ALK-1hasahighdegreeofsimilarityinserine-threoninekinasesuBDomains,aglycineandserinerichregionprecedingthekinase-domain,andaC-terminaltailwithotheractivinreceptor-likekinaseproteins.ALK-1ismainlyexpressedinendothelialcellsregulatingproliferationandmigrationinvitroandangiogenesisinvivo.MutationsinALK-1aswellasinendoglinareassociatedwithhereditaryhemorrhagictelangiectasia(HHT),suggestingALK-1playsacriticalroleforinthecontrolofbloodvesseldevelopmentorrepair. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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