Prosci/A1CF抗体/25-668/50微克
商品编号：
25-668
品牌：
prosci-inc
市场价：
¥6500.00
美元价：
3900.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIESREACTIVITY: | Human |
|---|---|
| TESTEDAPPLICATIONS: | ELISA,WB |
| APPLICATIONS: | A1CFantibodycanbeusedfordetectionofA1CFbyELISAat1:1562500.A1CFantibodycanbeusedfordetectionofA1CFbywesternblotat1μg/mL,andHRPconjugatedsecondaryantibodyshouldbediluted1:50,000-100,000. |
| USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
| POSITIVECONTROL: | 1)Cat.No.1211-HepG2CellLysate |
| PREDICTEDMOLECULARWEIGHT: | 65kDa |
| IMMUNOGEN: | AntibodyproducedinrabbitsimmunizedwithasyntheticpeptidecorrespondingaregionofhumanA1CF. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | Antibodyispurifiedbypeptideaffinitychromatographymethod. |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| BUFFER: | AntibodyislyophilizedinPBSbufferwith2%sucrose.Add50μLofdistilledwater.Finalantibodyconcentrationis1mg/mL. |
| CONCENTRATION: | 1mg/ml |
| STORAGECONDITIONS: | Forshortperiodsofstorage(days)storeat4˚C.Forlongerperiodsofstorage,storeA1CFantibodyat-20˚C.Aswithanyantibodyavoidrepeatfreeze-thawcycles. |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | A1CF,ACF,ACF64,ACF65,APOBEC1CF,ASP,MGC163391,RP11-564C4.2 |
|---|---|
| ACCESSIONNO.: | NP_620311 |
| PROTEINGINO.: | 20357578 |
| OFFICIALSYMBOL: | A1CF |
| GENEID: | 29974 |
Background
| BACKGROUND: | MammalianapolipoproteinBmRNAundergoessite-specificCtoUdeamination,whichismediatedbyamulti-componentenzymecomplexcontainingaminimalcorecomposedofAPOBEC-1andacomplementationfactorencodedbythisgene.A1CFhasthreenon-identicalRNArecognitionmotifsandbelongstothehnRNPRfamilyofRNA-bindingproteins.IthasbeenproposedthatthiscomplementationfactorfunctionsasanRNA-bindingsubunitanddocksAPOBEC-1todeaminatetheupstreamcytidine.StudiessuggestthattheproteinmayalsobeinvolvedinotherRNAeditingorRNAprocessingevents.Alternativesplicingoccursatthislocusandthreefull-lengthtranscriptvariants,encodingthreedistinctisoforms,havebeendescribed.Additionalsplicinghasbeenobservedbutthefull-lengthnatureofthesevariantshasnotbeendetermined.MammalianapolipoproteinBmRNAundergoessite-specificCtoUdeamination,whichismediatedbyamulti-componentenzymecomplexcontainingaminimalcorecomposedofAPOBEC-1andacomplementationfactorencodedbythisgene.Thegeneproducthasthreenon-identicalRNArecognitionmotifsandbelongstothehnRNPRfamilyofRNA-bindingproteins.IthasbeenproposedthatthiscomplementationfactorfunctionsasanRNA-bindingsubunitanddocksAPOBEC-1todeaminatetheupstreamcytidine.StudiessuggestthattheproteinmayalsobeinvolvedinotherRNAeditingorRNAprocessingevents.Alternativesplicingoccursatthislocusandthreefull-lengthtranscriptvariants,encodingthreedistinctisoforms,havebeendescribed.Additionalsplicinghasbeenobservedbutthefull-lengthnatureofthesevariantshasnotbeendetermined. |
|---|---|
| REFERENCES: | 1)Blanc,V.,(2005)Mol.Cell.Biol.25(16),7260-7269. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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