Prosci/ADAM17重组蛋白/96-968/50μg
商品编号：
96-968
品牌：
prosci-inc
市场价：
¥11500.00
美元价：
6900.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIES: | Mouse |
|---|---|
| SOURCE SPECIES: | HEK293 cells |
| SEQUENCE: | Pro 18 - Asp 563 |
| FUSION TAG: | His Tag |
| TESTED APPLICATIONS: | WB |
| APPLICATIONS: | This recombinant protein can be used for WB. For research use only. |
Properties
| PURITY: | >90% as determined by SDS-PAGE. Endotoxin level is less than 1.0 EU per ug by the LAL method. |
|---|---|
| PREDICTED MOLECULAR WEIGHT: | 63.4 kDa |
| PHYSICAL STATE: | Lyophilized |
| BUFFER: | 50 mM MES, 150 mM NaCl, pH6.5 |
| STORAGE CONDITIONS: | Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles. |
Additional Info
| ALTERNATE NAMES: | ADAM17,TACE,CD156b |
|---|---|
| ACCESSION NO.: | Q9Z0F8 |
Background
| Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17), a member of the ADAM protein family of disintegrins and metalloproteases, is also known as TNF-alpha convertase, TNF-alpha-converting enzyme and CD156b, which contains one disintegrin domain and one peptidase M12B domain. ADAM17 can cleave the membrane-bound precursor of TNF-alpha to its mature soluble form. ADAM17 is also responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity) and proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Furthermore, ADAM17 acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体，定制抗体开发服务和领先的研究计划可帮助科学家，实验室技术人员，研究人员和其他技术人员降低研究成本，灵活而广泛的抗体服务，在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
联络我们
