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Prosci/Activin Receptor IIB Recombinant Protein/91-282/0.05 mg
Prosci/Activin Receptor IIB Recombinant Protein/91-282/0.05 mg
商品编号:
91-282
品牌:
prosci-inc
市场价:
¥5500.00
美元价:
3300.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
SPECIES: | Human |
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SOURCE SPECIES: | Human Cells |
SEQUENCE: | Ser19-Thr134 |
FUSION TAG: | C-6 His tag |
TESTED APPLICATIONS: | |
APPLICATIONS: | This recombinant protein can be used for biological assays. For research use only. |
Properties
PURITY: | Greater than 95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
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PREDICTED MOLECULAR WEIGHT: | 14.37 kD |
PHYSICAL STATE: | Lyophilized |
BUFFER: | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. |
STORAGE CONDITIONS: | Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7˚C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚C for 3 months. |
Additional Info
ALTERNATE NAMES: | Activin Receptor Type-2B, Activin Receptor Type IIB, ACTR-IIB, ACVR2B, Activin RIIB |
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ACCESSION NO.: | Q13705 |
Background
Activin proteins that belong to the transforming growth factor-beta (TGF- beta ) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体,定制抗体开发服务和领先的研究计划可帮助科学家,实验室技术人员,研究人员和其他技术人员降低研究成本,灵活而广泛的抗体服务,在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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