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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prosci/Activin Receptor IIB Recombinant Protein/91-282/0.05 mg
商品详细Prosci/Activin Receptor IIB Recombinant Protein/91-282/0.05 mg
Prosci/Activin Receptor IIB Recombinant Protein/91-282/0.05 mg
Prosci/Activin Receptor IIB Recombinant Protein/91-282/0.05 mg
商品编号: 91-282
品牌: prosci-inc
市场价: ¥5500.00
美元价: 3300.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIES:Human
SOURCE SPECIES:Human Cells
SEQUENCE:Ser19-Thr134
FUSION TAG:C-6 His tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant protein can be used for biological assays. For research use only.

Properties

PURITY:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
PREDICTED MOLECULAR WEIGHT:14.37 kD
PHYSICAL STATE:Lyophilized
BUFFER:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
STORAGE CONDITIONS:Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Additional Info

ALTERNATE NAMES:Activin Receptor Type-2B, Activin Receptor Type IIB, ACTR-IIB, ACVR2B, Activin RIIB
ACCESSION NO.:Q13705

Background

Activin proteins that belong to the transforming growth factor-beta (TGF- beta ) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.
品牌介绍
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