4000-520-616
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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prosci/激活素A重组蛋白/40-213/0.01mg
商品详细Prosci/激活素A重组蛋白/40-213/0.01mg
Prosci/激活素A重组蛋白/40-213/0.01mg
Prosci/激活素A重组蛋白/40-213/0.01mg
商品编号: 40-213
品牌: prosci-inc
市场价: ¥4500.00
美元价: 2700.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Specifications

SPECIES:Human
SOURCESPECIES:E.coli
SEQUENCE:GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
TESTEDAPPLICATIONS:
BIOLOGICALACTIVITY:TheED50wasdeterminedbyitsABIlitytoinhibittheproliferationofmurineMPC-11cellsis≤2.0ng/mL,correspondingtoaspecificactivityof≥5x105units/mg.

Properties

PURITY:Greaterthan97%bySDS-PAGEgelandHPLCanalyses.

Endotoxinlevelislessthan0.1ngperμg(1EU/μg).
PHYSICALSTATE:Lyophilized
STORAGECONDITIONS:ThelyophilizedActivinArecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedActivinAisstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingActivinArecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature.

AdditionalInfo

ALTERNATENAMES:JV18,MADH2,MADR2,JV18-1,hMAD-2,hSMAD2,Mothersagainstdecapentaplegichomolog2,MADhomolog2
ACCESSIONNO.:NP_001003652.1
PROTEINGINO.:51173730

Background

ActivinAisaTGF-βfamilymemberthatexhibitsawiderangeofbiologicalactivitiesincludingregulationofcellularproliferationanddifferentiation,andpromotionofneuronalsurvival.ElevatedlevelsofActivinAinhumancolorectaltumorsandinpostmenopausalwomenhavebeenimplicatedincolorectalandbreastcancers,respectively.ThebiologicalactivitiesofActivinAcanbeneutralizedbyinhibinsandbythediffusIBLeTGF-βantagoNIST,follistatin.HumanActivinAisa26.0kDadisulfide-linkedhomodimeroftwoβAchains,eachcontaining116aminoacidresidues.
品牌介绍
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