Prosci/a连环蛋白(磷酸化Ser641)抗体/79-503/0.1mg
商品编号:
79-503
品牌:
prosci-inc
市场价:
¥6300.00
美元价:
3780.00
产品分类:
重组抗体
公司分类:
Recombinant_antibodies
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
SPECIES REACTIVITY: | Human, Mouse |
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TESTED APPLICATIONS: | WB |
APPLICATIONS: | Western Blot: 1:500~1:1000 |
PREDICTED MOLECULAR WEIGHT: | 100 kDa |
SPECIFICITY: | This antibody detects endogenous level of α-catenin only when phosphorylated at serine 641. |
IMMUNOGEN: | a-catenin (Phospho-Ser641) antibody was raised against a peptide sequence around phosphorylation site of serine 641 (D-D-S (p) -D-F) derived from Human α-catenin. |
HOST SPECIES: | Rabbit |
Properties
PURIFICATION: | Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
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PHYSICAL STATE: | Liquid |
BUFFER: | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
CONCENTRATION: | 1 mg/mL |
STORAGE CONDITIONS: | Store antibody at -20˚C for up to one year. |
CLONALITY: | Polyclonal |
CONJUGATE: | Unconjugated |
Additional Info
ALTERNATE NAMES: | CAP102, JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, Cadherin-associated protein, Alpha E-catenin, NY-REN-13 antigen |
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ACCESSION NO.: | NP_001894.2 |
PROTEIN GI NO.: | 55770844 |
OFFICIAL SYMBOL: | CTNNA1 |
GENE ID: | 1495 |
Background
BACKGROUND: | Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation. |
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REFERENCES: | 1) Hwang, S. G. et al. (2005) J. Biol. Chem. 280, 12758-12765Drees, F. et al. (2005) Cell 123, 903-915. Yamada, S. et al. (2005) Cell 123, 889-901. Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625. |
品牌介绍
ProSci我们是抗体开发公司中的领导者。我们的研究抗体,定制抗体开发服务和领先的研究计划可帮助科学家,实验室技术人员,研究人员和其他技术人员降低研究成本,灵活而广泛的抗体服务,在线支持以及丰富的抗体使用第一手知识因为它们与特定的免疫化学应用有关。
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