Prosci/4E-BP1（Ab 45）抗体/79-368/0.1mg
商品编号：
79-368
品牌：
prosci-inc
市场价：
¥6000.00
美元价：
3600.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
| SPECIESREACTIVITY: | Human,Mouse,Rat |
|---|---|
| TESTEDAPPLICATIONS: | IF,IHC,WB |
| APPLICATIONS: | WesternBlot:1:500~1:1000,Immunohistochemistry:1:50~1:100,Immunofluorescence:1:100~1:200 |
| PREDICTEDMOLECULARWEIGHT: | 18kDa |
| SPECIFICITY: | Thisantibodydetectsendogenousleveloftotal4E-BP1protein. |
| IMMUNOGEN: | 4E-BP1(Ab-45)antibodywasraisedagainstapeptidesequencearoundaa.43~47(S-T-T-P-G)derivedfromHuman4E-BP1. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | Antibodieswerepurifiedbyaffinity-chromatographyusingepitope-specificpeptide. |
|---|---|
| PHYSICALSTATE: | Liquid |
| BUFFER: | Antibodysuppliedinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| CONCENTRATION: | 1mg/mL |
| STORAGECONDITIONS: | Storeantibodyat-20˚Cforuptooneyear. |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | BP-1,4EBP1,4E-BP1,PHAS-I,FKHLA,EIF4EBP1,PHAS-1 |
|---|---|
| ACCESSIONNO.: | NP_004086.1 |
| PROTEINGINO.: | 4758258 |
| OFFICIALSYMBOL: | EIF4EBP1 |
| GENEID: | 1978 |
Background
| BACKGROUND: | 4E-BP1encodesonememberofafamilyoftranslationrepressorproteins.Theproteindirectlyinteractswitheukaryotictranslationinitiationfactor4E(eIF4E),whichisalimitingcomponentofthemultisubunitcomplexthatrecruits40Sribosomalsubunitstothe5"endofmRNAs.InteractionofthisproteinwitheIF4Einhibitscomplexassemblyandrepressestranslation.ThisproteinisphosphorylatedinresponsetovarioussignalsincludingUVirrADIationandinsulinsignaling,resultinginitsdissociationfromeIF4EandactivationofmRNAtranslation. |
|---|---|
| REFERENCES: | 1)GingrasAC,etal.(1998)GenesDev12(4):502-513.BrugarolasJ,etal.(2004)GenesDev18(23):2893-2904.KumarV,etal.(2000)EMBOJ19(5):1087-1097.MoodyCA,etal.(2005)JVirol79(9):5499-5506.BurnettPE,etal.(1998)ProcNatlAcadSciUSA95(4):1432-1437. |
品牌介绍
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